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1

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

Varjosalo, Markku, Sacco, Roberto, Stukalov, Alexey, van Drogen, Audrey, Planyavsky, Melanie, Hauri, Simon, Aebersold, Ruedi, Bennett, Keiryn L, Colinge, Jacques, Gstaiger, Matthias, Superti-Furga, Gi

Journal:

Year:

2013

Language:

english

File:

PDF, 766 KB

english, 2013

2

Recognition of Malondialdehyde-modified Proteins by the C Terminus of Complement Factor H Is Mediated via the Polyanion Binding Site and Impaired by Mutations Found in Atypical Hemolytic Uremic Syndrome

Hyvärinen, Satu, Uchida, Koji, Varjosalo, Markku, Jokela, Reija, Jokiranta, T. Sakari

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.72 MB

english, 2014

3

Expression of the Yersinia enterocolitica O:3 LPS O-antigen and outer core gene clusters is RfaH-dependent

Li, Chun-Mei, Varjosalo, Markku, Li, Zhilin, Leskinen, Katarzyna, Skurnik, Mikael

Journal:

Microbiology (Society for General Microbiology)

Year:

2015

Language:

english

File:

PDF, 2.21 MB

english, 2015

4

Predegenerated Schwann cells–a novel prospect for cell therapy for glaucoma: neuroprotection, neuroregeneration and neuroplasticity

Smedowski, Adrian, Liu, Xiaonan, Pietrucha-Dutczak, Marita, Matuszek, Iwona, Varjosalo, Markku, Lewin-Kowalik, Joanna

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 3.45 MB

english, 2016

5

Increased intraocular pressure alters the cellular distribution of HuR protein in retinal ganglion cells – A possible sign of endogenous neuroprotection failure

Smedowski, Adrian, Liu, Xiaonan, Podracka, Lucia, Akhtar, Saeed, Trzeciecka, Anna, Pietrucha-Dutczak, Marita, Lewin-Kowalik, Joanna, Urtti, Arto, Ruponen, Marika, Kaarniranta, Kai, Varjosalo, Markku,

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2018

Language:

english

File:

PDF, 2.31 MB

english, 2018

6

Probiotic supplementation restores normal microbiota composition and function in antibiotic-treated and in caesarean-born infants

Korpela, Katri, Salonen, Anne, Vepsäläinen, Outi, Suomalainen, Marjo, Kolmeder, Carolin, Varjosalo, Markku, Miettinen, Sini, Kukkonen, Kaarina, Savilahti, Erkki, Kuitunen, Mikael, de Vos, Willem M

Journal:

Year:

2018

Language:

english

File:

PDF, 1.37 MB

english, 2018

7

Design, Synthesis and Characterization of a PEGylated Stanozolol for Potential Therapeutic Applications

Vergallo, Cristian, Torrieri, Giulia, Provenzani, Riccardo, Miettinen, Sini, Moslova, Karina, Varjosalo, Markku, Chiara Cristiano, Maria, Fresta, Massimo, Celia, Christian, Santos, Hélder A., Cilurzo,

Journal:

International Journal of Pharmaceutics

Year:

2019

Language:

english

File:

PDF, 800 KB

english, 2019

8

High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections â Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils

Aaltonen, Niina, Singha, Prosanta K., JakupoviÄ, Hermina, Wirth, Thomas, Samaranayake, Haritha, Pasonen-SeppÃ¤nen, Sanna, Rilla, Kirsi, Varjosalo, Markku, Edgington-Mitchell, Laura E., Kasperkiewicz,

Journal:

Biological Procedures Online

Year:

2020

Language:

english

File:

PDF, 15.52 MB

english, 2020

9

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo

Wei, Gong-Hong, Badis, Gwenael, Berger, Michael F, Kivioja, Teemu, Palin, Kimmo, Enge, Martin, Bonke, Martin, Jolma, Arttu, Varjosalo, Markku, Gehrke, Andrew R

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 2.77 MB

english, 2010

10

Identification of pathways regulating cell size and cell-cycle progression by RNAi

Björklund, Mikael, Taipale, Minna, Varjosalo, Markku, Saharinen, Juha, Lahdenperä, Juhani, Taipale, Jussi

Journal:

Year:

2006

Language:

english

File:

PDF, 795 KB

english, 2006

11

Application of Active and Kinase-Deficient Kinome Collection for Identification of Kinases Regulating Hedgehog Signaling

Markku Varjosalo, Mikael Björklund, Fang Cheng, Heidi Syvänen, Teemu Kivioja, Sami Kilpinen, Zairen Sun, Olli Kallioniemi, Hendrik G. Stunnenberg, Wei-Wu He, Päivi Ojala, Jussi Taipale

Journal:

Year:

2008

Language:

english

File:

PDF, 2.19 MB

english, 2008

12

Divergence of Hedgehog Signal Transduction Mechanism between Drosophila and Mammals

Markku Varjosalo, Song-Ping Li, Jussi Taipale

Journal:

Developmental Cell

Year:

2006

Language:

english

File:

PDF, 631 KB

english, 2006

13

Regulation of PTEN activity by p38 -PKD1 signaling in neutrophils confers inflammatory responses in the lung

Ittner, A., Block, H., Reichel, C. A., Varjosalo, M., Gehart, H., Sumara, G., Gstaiger, M., Krombach, F., Zarbock, A., Ricci, R.

Journal:

Journal of Experimental Medicine

Year:

2012

Language:

english

File:

PDF, 3.91 MB

english, 2012

14

The Protein Interaction Landscape of the Human CMGC Kinase Group

Varjosalo, Markku, Keskitalo, Salla, Van Drogen, Audrey, Nurkkala, Helka, Vichalkovski, Anton, Aebersold, Ruedi, Gstaiger, Matthias

Journal:

Year:

2013

Language:

english

File:

PDF, 4.09 MB

english, 2013

15

Isolation, characterization and complete genome sequence of PhaxI: a phage of Escherichia coli O157 : H7

Shahrbabak, S. S., Khodabandehlou, Z., Shahverdi, A. R., Skurnik, M., Ackermann, H.-W., Varjosalo, M., Yazdi, M. T., Sepehrizadeh, Z.

Journal:

Microbiology (Society for General Microbiology)

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

16

Identification of Candidate Oncogenes in Human Colorectal Cancers With Microsatellite Instability

Gylfe, Alexandra E., Kondelin, Johanna, Turunen, Mikko, Ristolainen, Heikki, Katainen, Riku, Pitkänen, Esa, Kaasinen, Eevi, Rantanen, Ville, Tanskanen, Tomas, Varjosalo, Markku, Lehtonen, Heli, Palin,

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 2.30 MB

english, 2013

17

Protein Secretome of Moss Plants ( Physcomitrella patens ) with Emphasis on Changes Induced by a Fungal Elicitor

Lehtonen, Mikko T., Takikawa, Yoshihiro, Rönnholm, Gunilla, Akita, Motomu, Kalkkinen, Nisse, Ahola-Iivarinen, Elina, Somervuo, Panu, Varjosalo, Markku, Valkonen, Jari P. T.

Journal:

Journal of Proteome Research

Year:

2014

Language:

english

File:

PDF, 440 KB

english, 2014

18

Functional and Structural Properties of a Novel Protein and Virulence Factor (Protein sHIP) in Streptococcus pyogenes

Wisniewska, M., Happonen, L., Kahn, F., Varjosalo, M., Malmstrom, L., Rosenberger, G., Karlsson, C., Cazzamali, G., Pozdnyakova, I., Frick, I.-M., Bjorck, L., Streicher, W., Malmstrom, J., Wikstrom, M

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.46 MB

english, 2014

19

Hedgehog: functions and mechanisms

Varjosalo, M., Taipale, J.

Journal:

Genes & Development

Year:

2008

Language:

english

File:

PDF, 795 KB

english, 2008

20

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1

Hauri, Simon, Wepf, Alexander, van Drogen, Audrey, Varjosalo, Markku, Tapon, Nic, Aebersold, Ruedi, Gstaiger, Matthias

Journal:

Molecular Systems Biology

Year:

2013

Language:

english

File:

PDF, 915 KB

english, 2013

21

Gremlin-1 associates with fibrillin microfibrils in vivo and regulates mesothelioma cell survival through transcription factor slug

Tamminen, J A, Parviainen, V, Rönty, M, Wohl, A P, Murray, L, Joenväärä, S, Varjosalo, M, Leppäranta, O, Ritvos, O, Sengle, G, Renkonen, R, Myllärniemi, M, Koli, K

Journal:

Year:

2013

Language:

english

File:

PDF, 5.09 MB

english, 2013

22

FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complex

Sugiyama, N., Varjosalo, M., Meller, P., Lohi, J., Chan, K. M., Zhou, Z., Alitalo, K., Taipale, J., Keski-Oja, J., Lehti, K.

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 2.27 MB

english, 2010

23

Absence of YbeY RNase compromises the growth and enhances the virulence plasmid gene expression of Yersinia enterocolitica O:3

Leskinen, K., Varjosalo, M., Skurnik, M.

Journal:

Microbiology (Society for General Microbiology)

Year:

2015

Language:

english

File:

PDF, 749 KB

english, 2015

24

Navigating through metaproteomics data: A logbook of database searching

Muth, Thilo, Kolmeder, Carolin A., Salojärvi, Jarkko, Keskitalo, Salla, Varjosalo, Markku, Verdam, Froukje J., Rensen, Sander S., Reichl, Udo, de Vos, Willem M., Rapp, Erdmann, Martens, Lennart

Journal:

Year:

2015

Language:

english

File:

PDF, 1.11 MB

english, 2015

25

EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion

Sugiyama, N., Gucciardo, E., Tatti, O., Varjosalo, M., Hyytiainen, M., Gstaiger, M., Lehti, K.

Journal:

The Journal of Cell Biology

Year:

2013

Language:

english

File:

PDF, 7.04 MB

english, 2013

26

Hedgehog signaling

Varjosalo, M., Taipale, J.

Journal:

Journal of Cell Science

Year:

2006

Language:

english

File:

PDF, 348 KB

english, 2006

27

Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia

Saarikangas, J., Mattila, P. K., Varjosalo, M., Bovellan, M., Hakanen, J., Calzada-Wack, J., Tost, M., Jennen, L., Rathkolb, B., Hans, W., Horsch, M., Hyvonen, M. E., Perala, N., Fuchs, H., Gailus-Dur

Journal:

Journal of Cell Science

Year:

2011

Language:

english

File:

PDF, 3.99 MB

english, 2011

28

One-step Purification of Twin-Strep-tagged Proteins and Their Complexes on Strep-Tactin Resin Cross-linked With Bis(sulfosuccinimidyl) Suberate (BS3)

Ivanov, Konstantin I, Bašić, Marta, Varjosalo, Markku, Mäkinen, Kristiina

Journal:

Journal of Visualized Experiments

Year:

2014

Language:

english

File:

PDF, 1.72 MB

english, 2014

29

Rho-kinase inhibitor Y-27632 increases cellular proliferation and migration in human foreskin fibroblast cells

Piltti, Juha, Varjosalo, Markku, Qu, Chengjuan, Häyrinen, Jukka, Lammi, Mikko J.

Journal:

Year:

2015

Language:

english

File:

PDF, 921 KB

english, 2015

30

Human Receptors Patched and Smoothened Partially Transduce Hedgehog Signal When Expressed in Drosophila Cells

De Rivoyre, M., Ruel, L., Varjosalo, M., Loubat, A., Bidet, M., Therond, P., Mus-Veteau, I.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.46 MB

english, 2006

31

Fibroblast Growth Factor Receptor 4 Regulates Tumor Invasion by Coupling Fibroblast Growth Factor Signaling to Extracellular Matrix Degradation

Sugiyama, N., Varjosalo, M., Meller, P., Lohi, J., Hyytiainen, M., Kilpinen, S., Kallioniemi, O., Ingvarsen, S., Engelholm, L. H., Taipale, J., Alitalo, K., Keski-Oja, J., Lehti, K.

Journal:

Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.34 MB

english, 2010

32

KSHV Reactivation from Latency Requires Pim-1 and Pim-3 Kinases to Inactivate the Latency-Associated Nuclear Antigen LANA

Cheng, Fang, Weidner-Glunde, Magdalena, Varjosalo, Markku, Rainio, Eeva-Marja, Lehtonen, Anne, Schulz, Thomas F., Koskinen, Päivi J., Taipale, Jussi, Ojala, Päivi M., Früh, Klaus

Journal:

Year:

2009

Language:

english

File:

PDF, 864 KB

english, 2009

33

Bidirectional Interplay between Vimentin Intermediate Filaments and Contractile Actin Stress Fibers

Jiu, Yaming, Lehtimäki, Jaakko, Tojkander, Sari, Cheng, Fang, Jäälinoja, Harri, Liu, Xiaonan, Varjosalo, Markku, Eriksson, John E., Lappalainen, Pekka

Journal:

Year:

2015

Language:

english

File:

PDF, 3.45 MB

english, 2015

34

Quantitative Proteomics Analysis of Vitreous Humor from Diabetic Retinopathy Patients

Loukovaara, Sirpa, Nurkkala, Helka, Tamene, Fitsum, Gucciardo, Erika, Liu, Xiaonan, Repo, Pauliina, Lehti, Kaisa, Varjosalo, Markku

Journal:

Journal of Proteome Research

Year:

2015

Language:

english

File:

PDF, 4.60 MB

english, 2015

35

Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles

Haapasalo, Karita, van Kessel, Kok, Nissilä, Eija, Metso, Jari, Johansson, Tiira, Miettinen, Sini, Varjosalo, Markku, Kirveskari, Juha, Kuusela, Pentti, Chroni, Angelika, Jauhiainen, Matti, van Strijp

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

36

FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase–FGFR4 complex

Nami Sugiyama, Markku Varjosalo, Pipsa Meller, Jouko Lohi, Kui Ming Chan, Zhongjun Zhou, Kari Alitalo, Jussi Taipale, Jorma Keski-Oja, Kaisa Lehti and Joseph Schlessinger

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.77 MB

english, 2010

37

Molecular insights into the function of the viral RNA silencing suppressor HCPro

Ivanov, Konstantin I., Eskelin, Katri, Bašić, Marta, De, Swarnalok, Lõhmus, Andres, Varjosalo, Markku, Mäkinen, Kristiina

Journal:

The Plant Journal

Year:

2016

Language:

english

File:

PDF, 1.38 MB

english, 2016

38

Protein composition of 6K2-induced membrane structures formed during Potato virus A infection

Lõhmus, Andres, Varjosalo, Markku, Mäkinen, Kristiina

Journal:

Molecular Plant Pathology

Year:

2015

Language:

english

File:

PDF, 697 KB

english, 2015

39

Colonic metaproteomic signatures of active bacteria and the host in obesity

Kolmeder, Carolin A., Ritari, Jarmo, Verdam, Froukje J., Muth, Thilo, Keskitalo, Salla, Varjosalo, Markku, Fuentes, Susana, Greve, Jan Willem, Buurman, Wim A., Reichl, Udo, Rapp, Erdmann, Martens, Len

Journal:

Year:

2015

Language:

english

File:

PDF, 374 KB

english, 2015

40

Somatic MED12 exon 1 nonsense mutation in T-cell acute lymphoblastic leukemia escapes nonsense-mediated mRNA decay and prevents protein nuclear localization

Kämpjärvi, K., Heikkinen, T., Keskitalo, S., Von Nandelstadh, P., Rantanen, V., Pitkänen, E., Lehti, K., Mustjoki, S., Varjosalo, M., Vahteristo, P.

Journal:

European Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 61 KB

english, 2016

41

HB-GAM (pleiotrophin) reverses inhibition of neural regeneration by the CNS extracellular matrix

Paveliev, Mikhail, Fenrich, Keith K., Kislin, Mikhail, Kuja-Panula, Juha, Kulesskiy, Evgeny, Varjosalo, Markku, Kajander, Tommi, Mugantseva, Ekaterina, Ahonen-Bishopp, Anni, Khiroug, Leonard, Kulesska

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 3.14 MB

english, 2016

42

Several Hfq-dependent alterations in physiology of Yersinia enterocolitica O:3 are mediated by derepression of the transcriptional regulator RovM

Leskinen, Katarzyna, Pajunen, Maria I., Varjosalo, Markku, Fernández-Carrasco, Helena, Bengoechea, José A., Skurnik, Mikael

Journal:

Molecular Microbiology

Year:

2017

Language:

english

File:

PDF, 2.89 MB

english, 2017

43

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics

Yadav, Leena, Tamene, Fitsum, Göös, Helka, van Drogen, Audrey, Katainen, Riku, Aebersold, Ruedi, Gstaiger, Matthias, Varjosalo, Markku

Journal:

Year:

2017

Language:

english

File:

PDF, 2.51 MB

english, 2017

44

Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage

Pfisterer, Simon G., Gateva, Gergana, Horvath, Peter, Pirhonen, Juho, Salo, Veijo T., Karhinen, Leena, Varjosalo, Markku, Ryhänen, Samppa J., Lappalainen, Pekka, Ikonen, Elina

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 3.49 MB

english, 2017

45

Agonist-specific protein interactomes of glucocorticoid and androgen receptor as revealed by proximity mapping

Lempiäinen, Joanna K, Niskanen, Einari A, Vuoti, Kaisa-Mari, Lampinen, Riikka E, Göös, Helka, Varjosalo, Markku, Palvimo, Jorma J

Journal:

Molecular & Cellular Proteomics

Year:

2017

Language:

english

File:

PDF, 5.37 MB

english, 2017

46

PWP1 Mediates Nutrient-Dependent Growth Control through Nucleolar Regulation of Ribosomal Gene Expression

Liu, Ying, Mattila, Jaakko, Ventelä, Sami, Yadav, Leena, Zhang, Wei, Lamichane, Nicole, Sundström, Jari, Kauko, Otto, Grénman, Reidar, Varjosalo, Markku, Westermarck, Jukka, Hietakangas, Ville

Journal:

Developmental Cell

Year:

2017

Language:

english

File:

PDF, 3.10 MB

english, 2017

47

UNC-45a promotes myosin folding and stress fiber assembly

Lehtimäki, Jaakko I., Fenix, Aidan M., Kotila, Tommi M., Balistreri, Giuseppe, Paavolainen, Lassi, Varjosalo, Markku, Burnette, Dylan T., Lappalainen, Pekka

Journal:

The Journal of Cell Biology

Year:

2017

Language:

english

File:

PDF, 3.20 MB

english, 2017

48

Candidate proteins from predegenerated nerve exert time-specific protection of retinal ganglion cells in glaucoma

Pietrucha-Dutczak, Marita, Smedowski, Adrian, Liu, Xiaonan, Matuszek, Iwona, Varjosalo, Markku, Lewin-Kowalik, Joanna

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.32 MB

english, 2017

49

Systems pathology analysis identifies neurodegenerative nature of age-related vitreoretinal interface diseases

Öhman, Tiina, Tamene, Fitsum, Göös, Helka, Loukovaara, Sirpa, Varjosalo, Markku

Journal:

Year:

2018

Language:

english

File:

PDF, 2.68 MB

english, 2018

50

Redox regulation of GRPEL2 nucleotide exchange factor for mitochondrial HSP70 chaperone

Konovalova, Svetlana, Liu, Xiaonan, Manjunath, Pooja, Baral, Sundar, Neupane, Nirajan, Hilander, Taru, Yang, Yang, Balboa, Diego, Terzioglu, Mügen, Euro, Liliya, Varjosalo, Markku, Tyynismaa, Henna

Journal:

Year:

2018

Language:

english

File:

PDF, 1.71 MB

english, 2018

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